Sustainable Onshore Lobster Aquaculture
Sustainable Onshore Lobster Aquaculture

Neural remodelling in spiny lobster larvae is characterized by broad neuropeptide suppression

Abstract

Neuropeptides are ancient endocrine components which have evolved to regulate many aspects of biology across the animal kingdom including behaviour, development and metabolism. To supplement current knowledge, we have utilized a transcriptome series describing larval development in the ornate spiny lobster, Panulirus ornatus. The biology of this animal has been leveraged to provide insights into the roles of molting, metamorphosis and metabolism across the neuropeptide family. We report an extensive list of neuropeptides across three distinct life phases of the animal. We show distinct groups of neuropeptides with differential expression between larval phases, indicating phase-specific roles for these peptides. For selected neuropeptides, we describe and discuss expression profiles throughout larval development and report predicted peptide cleavage sites and mature peptide sequences. We also report the neuropeptide nesfatin for the first time in a crustacean, and report secondary peptide products with a level of evolutionary conservation similar to the conventional mature peptide nesfatin-1, indicating a conserved role in these secondary products which are widely regarded as biologically inactive. In addition, we report a trend of downregulation in the neuropeptides as the animal undergoes extensive neural remodelling in fulfillment of metamorphosis. We suggest that this downregulation in neuropeptides relates to the brief, yet dramatic changes in morphology experienced by the central nervous system in the process of metamorphosis. Copyright © 2020 Elsevier Inc. All rights reserved.

About

Research Hub Investigator(s)
Publication Year
2020
Citation
Hyde, C.J., Nguyen, T., Fitzgibbon, Q.P., Elizur, A., Smith, G.G. & Ventura, T. 2020, "Neural remodelling in spiny lobster larvae is characterized by broad neuropeptide suppression", General and comparative endocrinology, vol. 294, pp. 113496.
Link
Link to this Publication
Back to our Publication List
Sustainable Onshore Lobster AquacultureSustainable Onshore Lobster Aquaculture
The ARC Research Hub for Sustainable Onshore Lobster Aquaculture is funded by the Australian Government through the Australian Research Council Industrial Transformation Research Program. 

For more information about the Research Hub please contact us at Lobster.Aquaculture@utas.edu.au or phone +61 3 6226 8268.
Australian Research CouncilInstitute of Marine and Antarctic StudiesUniversity of TasmaniaOrnatasUniversity of Sunshine CoastPFG GroupUniversity of New Zealand
Copyright 2021 ARC Research Hub for Sustainable Onshore Lobster Aquaculture.
Top linkedin facebook pinterest youtube rss twitter instagram facebook-blank rss-blank linkedin-blank pinterest youtube twitter instagram